Wednesday, May 5, 2010

More information on Sjogren's Syndrome

Henrik Sjogren was a Swedish ophthalmologist and the first to recongnize that dry eyes and dry mouth were often found in people with connective tissue diseases. At any given time,the combination of problems encountered by the patient may vary considerably, from no active blood features of one ,two, or all three of these conditions at the same time. These persons often (but not always) have one specific blood antibody in their blood (anti-U1RNP antibody) but not the other antibodies associated with SLE, SSc, or PM-DM. Whether this is an entirely separate disease, or a situation in which one person has three diseases,remains uncertain. However, the presence of a single individualized and directed at the particular problems present at any given time. Sjogren's Syndrome also occurs in some people with lupus. They have an increased frequency of sun-sensitive rashes and Sjogren's related blood antibodies (anti-SSA and anti-SSB antibodies). Women with anti-SSA antibodies are at increased risk of having babies with "neonatal lupus" Symptoms in the infant can be as minor as a temporary lupus-like skin rash, or as serious as permanent damage to the electrical system of the heart which results in a very slow heart rate (complete heart block).

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